Considering the molecule N-[(2-hydroxy-3-methoxyphenyl)methyl]-N-(4-methylphenyl)-acetamide.

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October 30, 2020
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October 30, 2020

Considering the molecule N-[(2-hydroxy-3-methoxyphenyl)methyl]-N-(4-methylphenyl)-acetamide.

Considering the molecule N-[(2-hydroxy-3-methoxyphenyl)methyl]-N-(4-methylphenyl)-acetamide. How could the N-atom lone pair in the imine affect H-NMR chemical shifts of H-atoms that are ortho and meta to the N-atom (relative to benzene)? Would it have something to do with natural bond orbitals or the type of directing group it would be?

 

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